Translational Modulation of Proteins Expressed from Bicistronic Vectors
نویسندگان
چکیده
منابع مشابه
Translational efficiency of EMCV IRES in bicistronic vectors is dependent upon IRES sequence and gene location.
The internal ribosomal entry site (IRES)from encephalomyocarditis virus (EMCV) is a popular RNA element used widely in experimental and pharmaceutical applications to express proteins in eukaryotic cells or cell-free extracts. Inclusion of the wild-type element in monocistronic or bicistronic messenger RNAs (mRNAs) confers a high level of cap-independent translation activity to appropriately co...
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ژورنال
عنوان ژورنال: Molecular Imaging
سال: 2009
ISSN: 1536-0121,1536-0121
DOI: 10.2310/7290.2009.00028